Description

7-Methoxy-1H-Indole-2-Boronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic organic chemistry, particularly in cross-coupling reactions. This compound serves as a critical building block for constructing complex molecular architectures, offering enhanced stability and handling compared to its free boronic acid counterpart. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel indole-based compounds.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially those containing functionalized indole scaffolds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require specific indole motifs for biological activity.
• Material Science: Employed in the synthesis of organic semiconductors, ligands for catalysts, and other functional organic materials.
• Chemical Biology: Acts as a versatile handle for bioconjugation and the synthesis of molecular probes and inhibitors for biological studies.
• Academic & Contract Research: A valuable reagent for methodological development and the synthesis of complex natural product analogs in research laboratories.

Basic Information

Product Name	7-Methoxy-1H-Indole-2-Boronic Acid Pinacol Ester
CAS No.	1072812-69-1
Molecular Formula	C15H20BNO3
Molecular Weight	273.14 g/mol
Synonyms	7-Methoxy-1H-indol-2-ylboronic acid pinacol ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-7-methoxy-1H-indole; 7-Methoxyindole-2-boronic acid pinacol ester; 7-Methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole; 1H-Indole-2-boronic acid, 7-methoxy-, 1,1-dimethylethyl ester; B-(7-Methoxy-1H-indol-2-yl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 7-Methoxy-1H-Indole-2-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C) under an inert atmosphere if possible. The container should be kept in a well-ventilated area. Keep away from heat and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.