Description

3-Methyl-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Indole CAS NO 1072812-35-1 is a high-value indole-based boronic ester building block, essential for modern synthetic organic chemistry. This compound serves as a critical intermediate in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for applications in drug discovery, agrochemical development, and advanced material science.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates via Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of advanced crop protection agents and herbicides.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport materials.
• Ligand and Catalyst Development: Employed in the design and synthesis of novel ligands and organometallic catalysts.
• Chemical Biology Probes: Utilized for labeling and modifying biomolecules in proteomics and diagnostic assay development.
• Academic & Industrial R&D: A versatile reagent for methodological development in organic synthesis and medicinal chemistry programs.

Basic Information

Product Name	3-Methyl-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Indole
CAS No.	1072812-35-1
Molecular Formula	C15H20BNO2
Molecular Weight	257.14 g/mol
Synonyms	2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-methyl-1H-indole; 3-Methyl-1H-indole-2-boronic acid pinacol ester; 3-Methylindole-2-boronic acid pinacol ester; 1H-Indole-2-boronic acid, 3-methyl-, 1,1,1,1-tetramethyl ester; 1072812-35-1; 3-Methyl-2-(pinacolatoboryl)-1H-indole
EINECS	Contact for details

Quality Control

Our 3-Methyl-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Indole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry verification. Certificates of Analysis (COA) are available for every batch upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry place. This product is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air and moisture must be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.