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7-Bromo-1H-Indole-2-Boronic Acid Pinacol Ester CAS NO 1072812-23-7


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CAS No.:1072812-23-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

7-Bromo-1H-Indole-2-Boronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex indole-based molecular architectures. It is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and development programs.

Application

  • Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly those containing functionalized indole scaffolds.
  • Agrochemical Research: Used in the development of new active ingredients for crop protection by constructing complex heterocyclic systems.
  • Material Science: Employed in the synthesis of organic electronic materials, such as OLEDs and semiconductors, where precise molecular engineering is required.
  • Chemical Biology: Acts as a versatile handle for bioconjugation and the synthesis of molecular probes for studying biological systems.
  • Academic & Contract Research: A valuable reagent for methodological development in organic synthesis and for producing custom compounds in research laboratories.

Basic Information

Product Name 7-Bromo-1H-Indole-2-Boronic Acid Pinacol Ester
CAS No. 1072812-23-7
Molecular Formula C₁₄H₁₇BBrNO₂
Molecular Weight 322.01 g/mol
Synonyms 7-Bromo-1H-indole-2-boronic acid pinacol ester; 2-(7-Bromo-1H-indol-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 7-Bromoindole-2-boronic acid pinacol ester; (7-Bromo-1H-indol-2-yl)boronic acid pinacol ester; B-(7-Bromo-1H-indol-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 7-Bromo-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole; 1072812-23-7
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Quality Control

Our 7-Bromo-1H-Indole-2-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure should be avoided to maintain stability.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (HPLC) Conforms
Identification (NMR) Conforms
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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