Description

4-Methyl-1H-Indole-2-Boronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers for the synthesis of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing indole-based drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides with complex heterocyclic structures.
• Material Science Research: Employed in the synthesis of organic semiconductors, ligands for catalysts, and other functional organic materials.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of molecular probes and inhibitors.
• Academic & Contract Research: Serves as a fundamental reagent in university laboratories and CROs (Contract Research Organizations) for methodological development and library synthesis.

Basic Information

Product Name	4-Methyl-1H-Indole-2-Boronic Acid Pinacol Ester
CAS No.	1072811-23-4
Molecular Formula	C15H20BNO2
Molecular Weight	257.14 g/mol
Synonyms	4-Methyl-1H-indole-2-boronic acid pinacol ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-methyl-1H-indole; 4-Methylindole-2-boronic acid pinacol ester; 4-Methyl-1H-indol-2-ylboronic acid pinacol ester; (4-Methyl-1H-indol-2-yl)boronic acid pinacol ester; PINACOL 4-METHYL-1H-INDOLE-2-BORONATE; 1072811-23-4
EINECS	Contact for details

Quality Control

Every batch of 4-Methyl-1H-Indole-2-Boronic Acid Pinacol Ester is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee batch-to-batch consistency and traceability for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.