Description

4-Methoxy-1H-Indole-2-Boronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative crucial for modern synthetic chemistry. This compound serves as a key building block in cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers for the synthesis of novel active pharmaceutical ingredients (APIs) and advanced organic materials.

Application

• Pharmaceutical Intermediate: A critical precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing complex indole-based drug candidates.
• Agrochemical Research: Used in the development of novel herbicides and fungicides containing functionalized indole structures.
• Material Science: Building block for creating organic semiconductors and advanced polymers with specific electronic properties.
• Academic & Contract Research: Essential reagent for methodological development in organic synthesis and medicinal chemistry programs.
• Peptide Mimetics: Facilitates the introduction of the 4-methoxyindole moiety into peptide backbones for bioactivity studies.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	4-Methoxy-1H-Indole-2-Boronic Acid Pinacol Ester
CAS No.	1072811-21-2
Molecular Formula	C₁₅H₂₀BNO₃
Molecular Weight	273.14 g/mol
Synonyms	4-Methoxy-1H-indole-2-boronic acid pinacol ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-methoxy-1H-indole; 4-Methoxyindole-2-boronic acid pinacol ester; 4-Methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole; B-(4-Methoxy-1H-indol-2-yl)boronic acid pinacol ester; 1072811-21-2; 4-Methoxy-1H-indol-2-ylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 4-Methoxy-1H-Indole-2-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.