Description

tert-Butyl n-[2-(Oxiran-2-Yl)Ethyl]Carbamate is a high-purity, specialized organic building block featuring both a protected amine (Boc group) and a reactive epoxide (oxirane) moiety. This bifunctional nature makes it a critical intermediate for the synthesis of complex molecules, enabling the controlled introduction of amine functionality into target structures. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams for constructing active pharmaceutical ingredients (APIs), peptide mimetics, and advanced material linkers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and CNS drug discovery.
• Peptide Chemistry: Used to introduce protected aminoethyl linkers or create conformationally constrained peptide analogs via epoxide ring-opening reactions.
• Bioconjugation & ADC Development: Serves as a linker precursor for Antibody-Drug Conjugates (ADCs), connecting cytotoxic payloads to targeting antibodies.
• Polymer & Material Science: Monomer for synthesizing functionalized polymers, epoxy resins, and hydrogels with amine-reactive sites.
• Chemical Biology Probes: Enables the labeling and study of biological targets through its reactive epoxide group.
• Custom Synthesis & CRO Services: A valuable starting material for contract research organizations (CROs) and fine chemical manufacturers performing bespoke synthesis.

Basic Information

Product Name	tert-Butyl n-[2-(Oxiran-2-Yl)Ethyl]Carbamate
CAS No.	1072793-83-9
Molecular Formula	C9H17NO3
Molecular Weight	187.24 g/mol
Synonyms	tert-Butyl (2-(oxiran-2-yl)ethyl)carbamate; 2-[(tert-Butoxycarbonyl)amino]ethyloxirane; N-Boc-2-aminoethyloxirane; N-(tert-Butoxycarbonyl)-2-aminoethyloxirane; tert-Butyl (2-(2-oxiranyl)ethyl)carbamate; Boc-AEE; Boc-2-Aminoethyl Glycidyl Ether; Glycidyl N-Boc-ethylamine
EINECS	Contact for details

Quality Control

Our tert-Butyl n-[2-(Oxiran-2-Yl)Ethyl]Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.