Description

6-Fluoro-2,3-Dihydrobenzofuran is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce fluorine atoms or the dihydrobenzofuran scaffold into target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, especially in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atom can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a building block for specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research: Employed in academic and industrial laboratories for method development and exploration of new fluorination chemistry.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Product Name	6-Fluoro-2,3-Dihydrobenzofuran
CAS No.	1072153-65-1
Molecular Formula	C8H7FO
Molecular Weight	138.14 g/mol
Synonyms	6-Fluoro-2,3-dihydro-1-benzofuran; 2,3-Dihydro-6-fluorobenzofuran; 6-Fluorodihydrobenzofuran; 6-Fluoro-2,3-dihydrobenzofurane; 6-Fluoro-2,3-dihydro-benzo[b]furan; 1072153-65-1; 6-Fluoro-2,3-dihydro-1H-benzofuran
EINECS	Contact for details

Quality Control

Our 6-Fluoro-2,3-Dihydrobenzofuran is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.