Description

2-(3,5-Di-tert-Butylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity, advanced boronic ester intermediate essential for modern synthetic chemistry. This compound matters for its critical role in facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. Pharmaceutical, agrochemical, and advanced materials researchers need it for the efficient synthesis of novel active ingredients and functional molecules. Its stability and reactivity profile make it a preferred building block for demanding R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for manufacturing electron-transport materials and emissive layer components.
• Polymer & Material Science: Enables the production of specialty polymers, liquid crystals, and advanced organic frameworks with tailored properties.
• Chemical Research & Development: A versatile reagent in academic and industrial labs for methodology development and complex molecule construction.
• Ligand & Catalyst Preparation: Used to synthesize sophisticated ligands and organometallic catalysts for asymmetric synthesis.

Basic Information

Product Name	2-(3,5-Di-tert-Butylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1071924-13-4
Molecular Formula	C20H33BO2
Molecular Weight	316.29 g/mol
Synonyms	2-(3,5-Di-tert-butylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3,5-Di-tert-butylbenzeneboronic acid pinacol ester; (3,5-Bis(1,1-dimethylethyl)phenyl)boronic acid pinacol ester; 2-(3,5-Di-tert-butylphenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane; 3,5-Di-tert-butylphenylboronic acid pinacol ester; 1071924-13-4; AKOS BRN-0839; BRN 0839
EINECS	Contact for details

Quality Control

Our 2-(3,5-Di-tert-Butylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive applications. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to confirm identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with REACH and other relevant global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged operations to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.