Description

2-(6-Bromo-2-Fluoro-3-Methoxyphenyl)-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its role as a key intermediate for constructing complex molecules via cross-coupling reactions, offering a stable and reactive handle for further functionalization. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs) via Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific halogenated aryl structures.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as OLEDs and semiconductors, where precise molecular architecture is key.
• Chemical Biology & Probe Development: Employed in the creation of molecular probes and bioconjugates for diagnostic and research applications.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic synthesis and catalysis studies.
• Fine Chemical Production: Used in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	2-(6-Bromo-2-Fluoro-3-Methoxyphenyl)-1,3,2-Dioxaborolane
CAS No.	1070871-08-7
Molecular Formula	C10H11BBrFO3
Molecular Weight	287.91 g/mol
Synonyms	6-Bromo-2-fluoro-3-methoxyphenylboronic acid, pinacol ester; (6-Bromo-2-fluoro-3-methoxyphenyl)boronic acid pinacol ester; 2-Fluoro-6-bromo-3-methoxyphenylboronic acid pinacol ester; B-(6-Bromo-2-fluoro-3-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol (6-Bromo-2-fluoro-3-methoxyphenyl)boronate; 1070871-08-7; Boronic acid, B-(6-bromo-2-fluoro-3-methoxyphenyl)-, 4,4,5,5-tetramethyl-1,3,2-dioxaborolane ester
EINECS	Contact for details

Quality Control

Our 2-(6-Bromo-2-Fluoro-3-Methoxyphenyl)-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment supports applications requiring stringent material consistency, from early-stage R&D to cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.