Description

(E)-Ethyl 2-Methyl-3-Nitroacrylate is a versatile, high-purity nitroacrylate derivative, a crucial building block in advanced organic synthesis. Its value lies in its unique α,β-unsaturated nitroester structure, which makes it a highly reactive Michael acceptor and a key intermediate for constructing complex nitrogen-containing heterocycles. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of pyrrole, pyrrolidine, and other nitrogen-based heterocyclic scaffolds prevalent in drug discovery programs.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and insecticides, leveraging its nitro group for bioactivity.
• Fine Chemical Building Block: Serves as a precursor for dyes, pigments, and specialty polymers requiring specific nitro-functionalized monomers.
• Material Science Research: Investigated for use in nonlinear optical (NLO) materials and as a component in advanced polymer composites.
• Academic & R&D: Employed in methodological studies of conjugate addition reactions, cycloadditions, and other nitroalkene chemistry.

Basic Information

Product Name	(E)-Ethyl 2-Methyl-3-Nitroacrylate
CAS No.	1070237-84-1
Molecular Formula	C7H11NO4
Molecular Weight	173.17 g/mol
Synonyms	Ethyl (E)-2-Methyl-3-nitroacrylate; (E)-Ethyl 2-Methyl-3-nitro-2-propenoate; 2-Propenoic acid, 2-methyl-3-nitro-, ethyl ester, (2E)-; Ethyl (E)-2-methyl-3-nitropropenoate; 3-Nitroacrylic acid ethyl ester, 2-methyl-; Ethyl 2-methyl-3-nitroacrylate (E-isomer); NSC 406309; AI3-52300
EINECS	Contact for details

Quality Control

Every batch of (E)-Ethyl 2-Methyl-3-Nitroacrylate is manufactured and tested under strict quality management systems. We ensure high chemical purity and isomeric consistency through advanced analytical techniques including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from heat, sparks, and open flame. For long-term storage, consider packaging under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Typical 98-99%)
Isomeric Purity ((E)-isomer)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.