Description

1-Bromo-5-Chloro-4-Fluoro-2-Iodobenzene is a highly functionalized halogenated benzene derivative, serving as a critical multi-purpose building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogen functionalities into their target structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially those requiring specific halogen atoms for bioactivity or as synthetic handles for further functionalization.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the halogen pattern influences biological activity and environmental stability.
• Material Science: Serves as a monomer or building block for creating specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for various metal-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Sonogashira) due to the presence of reactive bromo and iodo groups.
• Ligand and Catalyst Development: Utilized in the preparation of sophisticated ligands for catalysis and molecular recognition studies.
• Chemical Research & Development: A versatile reagent for exploring new synthetic methodologies and constructing molecular libraries for screening.

Basic Information

Product Name	1-Bromo-5-Chloro-4-Fluoro-2-Iodobenzene
CAS No.	1067882-65-8
Molecular Formula	C6H2BrClFI
Molecular Weight	335.34 g/mol
Synonyms	2-Bromo-4-Chloro-5-Fluoro-1-Iodobenzene; 4-Bromo-2-Chloro-1-Fluoro-5-Iodobenzene; 1-Iodo-2-Bromo-4-Chloro-5-Fluorobenzene; Benzene, 1-bromo-5-chloro-4-fluoro-2-iodo-; 5-Chloro-4-fluoro-2-iodo-1-bromobenzene; 2-Bromo-5-chloro-4-fluoro-1-iodobenzene
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is analyzed to confirm identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data. Our quality management system is designed to meet the stringent requirements of research and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Recommended storage temperature is between 2°C and 8°C for long-term stability, although the product is stable at controlled room temperature for shorter periods. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.