Description

4-(2-Fluorophenyl)-1H-1,2,4-Triazol-5(4H)-One is a specialized fluorinated heterocyclic compound belonging to the 1,2,4-triazolone class, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular architecture, which incorporates both a fluorinated aromatic ring and a versatile triazolone moiety, making it an essential intermediate for developing novel active compounds. This high-purity intermediate is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-infectives, and metabolic diseases.
• Agrochemical Synthesis: Used as a precursor in the design and synthesis of novel herbicides, fungicides, and insecticides, where the fluorine atom and triazole ring can enhance biological activity and environmental stability.
• Chemical Research & Development: Serves as a versatile scaffold in academic and industrial R&D for exploring new chemical entities, structure-activity relationships (SAR), and heterocyclic chemistry.
• Material Science Precursor: Potential use in the synthesis of advanced organic materials, such as ligands for catalysts or components for specialty polymers, due to its rigid, functionalized structure.

Basic Information

Product Name	4-(2-Fluorophenyl)-1H-1,2,4-Triazol-5(4H)-One
CAS No.	1065074-15-8
Molecular Formula	C8H6FN3O
Molecular Weight	179.15 g/mol
Synonyms	4-(2-Fluorophenyl)-4H-1,2,4-triazol-5-one; 1H-1,2,4-Triazol-5(4H)-one, 4-(2-fluorophenyl)-; 4-(2-Fluorophenyl)-1,2,4-triazol-5-one; 4-(2-Fluorophenyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole; 2-Fluorophenyl-1,2,4-triazol-5-one; 4-(o-Fluorophenyl)-1H-1,2,4-triazol-5(4H)-one
EINECS	Contact for details

Quality Control

Our 4-(2-Fluorophenyl)-1H-1,2,4-Triazol-5(4H)-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and synthesis. Each lot undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to meet the exacting standards required for advanced chemical intermediates. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.