Description

4-Aminopyridine-2-Boronic Acid Pinacol Ester is a high-value, multifunctional boronic ester derivative that serves as a critical building block in modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of pharmaceutical and advanced materials research. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to construct complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology & Proteomics: Utilized in the development of molecular probes and bioconjugation reagents for target identification and validation.
• Cross-Coupling Reactions: A versatile coupling partner in palladium-catalyzed Suzuki-Miyaura reactions for constructing biaryl and heterobiaryl structures.
• Academic & Contract Research: Fundamental reagent for methodology development and library synthesis in academic and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	4-Aminopyridine-2-Boronic Acid Pinacol Ester
CAS No.	1061750-57-9
Molecular Formula	C11H17BN2O2
Molecular Weight	220.08 g/mol
Synonyms	2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-aminopyridine; 4-Amino-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 4-Amino-2-pyridinylboronic acid pinacol ester; 4-Aminopyridine-2-boronic acid pinacol ester; 2-(4-Aminopyridin-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Amino-2-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
EINECS	Contact for details

Quality Control

Our 4-Aminopyridine-2-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.