Description

2-(2-Chloro-6-Methoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient and selective cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries, where it serves as a key intermediate in the development of active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in creating biaryl structures common in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides, leveraging its reactivity to introduce complex phenyl moieties.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and organic semiconductors.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and labeled compounds for biochemical assays and diagnostic research.
• Academic & Process R&D: A valuable reagent for method development and scaling up synthetic routes in both academic laboratories and industrial process chemistry.
• Ligand & Catalyst Synthesis: Used to prepare sophisticated ligands and organometallic catalysts for asymmetric synthesis and other catalytic applications.

Basic Information

Product Name	2-(2-Chloro-6-Methoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1061367-22-3
Molecular Formula	C13H18BClO3
Molecular Weight	268.54 g/mol
Synonyms	2-(2-Chloro-6-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (2-Chloro-6-methoxyphenyl)boronic acid pinacol ester; 2-Chloro-6-methoxybenzeneboronic acid pinacol ester; Pinacol (2-chloro-6-methoxyphenyl)boronate; 2-Chloro-6-methoxyphenylboronic acid pinacol ester; 1,3,2-Dioxaborolane, 2-(2-chloro-6-methoxyphenyl)-4,4,5,5-tetramethyl-; B-(2-Chloro-6-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 2-(2-Chloro-6-Methoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment supports applications requiring GMP and ISO-aligned standards for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0% (Area %)
Purity (GC)	≥96.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.