Description

Oxazole, 2-Bromo-4-(Trifluoromethyl)- is a high-value, multi-functional heterocyclic building block distinguished by its bromo and trifluoromethyl substituents. This compound is critical for researchers and process chemists seeking to introduce these pharmacologically important motifs into target molecules with precision. It is primarily utilized in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as in advanced material science for creating specialty polymers and electronic materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, antiviral agents, and anti-inflammatory compounds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Precursor: Serves as a building block for synthesizing specialty polymers, liquid crystals, and organic electronic materials requiring specific optoelectronic properties.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) to create complex molecular architectures.
• Fluorine Chemistry Research: An essential reagent for studying the effects of fluorine incorporation on molecular properties like lipophilicity, bioavailability, and chemical stability.
• Chemical Library Development: Employed in high-throughput and combinatorial chemistry to generate diverse compound libraries for biological screening.

Basic Information

Item	Detail
Product Name	Oxazole, 2-Bromo-4-(Trifluoromethyl)-
CAS No.	1060816-14-9
Molecular Formula	C4H1BrF3NO
Molecular Weight	215.96 g/mol
Synonyms	2-Bromo-4-(trifluoromethyl)oxazole; 4-(Trifluoromethyl)-2-bromooxazole; 2-Bromo-4-trifluoromethyloxazole; Oxazole, 2-bromo-4-(trifluoromethyl)-; Bromo(trifluoromethyl)oxazole; 2-Bromo-4-(trifluoromethyl)-1,3-oxazole
EINECS	Contact for details

Quality Control

Every batch of Oxazole, 2-Bromo-4-(Trifluoromethyl)- is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency essential for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.