Description

Ethyl 4-Ethynylbenzoate is a high-purity organic building block featuring both an ethynyl and an ester functional group. This compound is valued for its role as a versatile intermediate in advanced organic synthesis, particularly in click chemistry and cross-coupling reactions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of targeted drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Material Science & Polymer Chemistry: Serves as a monomer or cross-linking agent for creating specialty polymers, dendrimers, and advanced materials with tailored properties.
• Click Chemistry Reagent: The terminal alkyne group makes it an ideal substrate for Huisgen cycloaddition (copper-catalyzed azide-alkyne cycloaddition) reactions.
• Liquid Crystal & OLED Research: Used as a precursor in the synthesis of organic electronic materials and liquid crystal compounds.
• Cross-Coupling Reactions: Acts as a coupling partner in Sonogashira, Heck, and other palladium-catalyzed reactions to construct complex molecular architectures.

Basic Information

Item	Detail
Product Name	Ethyl 4-Ethynylbenzoate
CAS No.	1060816-03-6
Molecular Formula	C11H10O2
Molecular Weight	174.20 g/mol
Synonyms	4-Ethynylbenzoic Acid Ethyl Ester; Ethyl p-Ethynylbenzoate; Benzoic acid, 4-ethynyl-, ethyl ester; Ethyl 4-ethynylbenzoate; p-Ethynylbenzoic Acid Ethyl Ester; 1060816-03-6; Ethyl (4-ethynylphenyl)formate
EINECS	Contact for details

Quality Control

Our Ethyl 4-Ethynylbenzoate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high chemical purity and structural identity. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.