Description

4-Bromo-6-Chloropicolinaldehyde is a versatile and high-purity halogenated picolinaldehyde derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its reactive aldehyde and halogen functional groups, enabling precise molecular construction for complex target compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality raw materials for developing active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating complex chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the construction of organic electronic materials, such as ligands for OLEDs and conductive polymers.
• Chemical Biology Probes: Utilized to synthesize molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis and R&D: An invaluable building block for contract research organizations (CROs) and R&D departments exploring new chemical entities.

Basic Information

Product Name	4-Bromo-6-Chloropicolinaldehyde
CAS No.	1060811-63-3
Molecular Formula	C6H3BrClNO
Molecular Weight	220.45 g/mol
Synonyms	6-Chloro-4-bromopicolinaldehyde; 4-Bromo-6-chloro-2-pyridinecarboxaldehyde; 2-Pyridinecarboxaldehyde, 4-bromo-6-chloro-; 4-Bromo-6-chloropyridine-2-carbaldehyde; Picolinaldehyde, 4-bromo-6-chloro-; 4-Bromo-6-chloro-2-formylpyridine; 2-Formyl-4-bromo-6-chloropyridine
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-6-Chloropicolinaldehyde is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring the material meets the stringent requirements of advanced R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.