Description

4-Amino-6-Bromo-Pyridine-2-Carbaldehyde is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters for its unique bifunctional reactivity, offering both an aldehyde and an amino group on a brominated pyridine scaffold, which enables precise molecular construction. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted small-molecule therapeutics.
• Agrochemical Research: Used to develop new active ingredients for crop protection products, leveraging its halogen and nitrogen-containing structure.
• Ligand Synthesis: Serves as a versatile starting material for creating complex chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Functional Material Development: Employed in the research and production of advanced organic electronic materials and dyes.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig).
• Academic & Contract Research: A valuable reagent for methodological studies and custom synthesis projects in university and CRO laboratories.

Basic Information

Product Name	4-Amino-6-Bromo-Pyridine-2-Carbaldehyde
CAS No.	1060809-66-6
Molecular Formula	C6H5BrN2O
Molecular Weight	201.02 g/mol
Synonyms	6-Bromo-4-aminopyridine-2-carboxaldehyde; 2-Formyl-6-bromo-4-aminopyridine; 4-Amino-6-bromopicolinaldehyde; 6-Bromo-4-amino-2-pyridinecarboxaldehyde; 4-Amino-6-bromo-2-formylpyridine; 2-Pyridinecarboxaldehyde, 4-amino-6-bromo-; 1060809-66-6 (CAS)
EINECS	Contact for details

Quality Control

Our 4-Amino-6-Bromo-Pyridine-2-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after opening the primary container. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.