Description

2,2,2-Trifluoro-1-(6-Methylpyridin-2-Yl)Ethanone is a high-purity fluorinated pyridine derivative, a key building block in advanced organic synthesis. Its trifluoroacetyl group adjacent to a methylpyridine scaffold makes it a versatile intermediate for introducing fluorine atoms into complex molecular architectures. This compound is primarily sought by pharmaceutical and agrochemical R&D sectors for the development of novel active ingredients, where its unique structure can impart enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of fluorinated drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides and pesticides, where the fluorine atoms enhance lipophilicity and biological activity.
• Material Science Precursor: Serves as a starting material for synthesizing specialized ligands, catalysts, and fluorinated polymers with unique electronic properties.
• Chemical Research & Development: Employed in academic and industrial labs for method development and exploring new fluorination reactions and heterocyclic chemistry.

Basic Information

Product Name	2,2,2-Trifluoro-1-(6-Methylpyridin-2-Yl)Ethanone
CAS No.	1060806-26-9
Molecular Formula	C8H6F3NO
Molecular Weight	189.13 g/mol
Synonyms	2,2,2-Trifluoro-1-(6-methyl-2-pyridinyl)ethanone; 1-(6-Methylpyridin-2-yl)-2,2,2-trifluoroethanone; 6-Methyl-2-(trifluoroacetyl)pyridine; 2-Acetyl-6-methylpyridine trifluoromethyl ketone; 2,2,2-Trifluoro-1-(6-methyl-2-pyridyl)ethanone; Trifluoroacetyl-6-methylpyridine
EINECS	Contact for details

Quality Control

Our production of 2,2,2-Trifluoro-1-(6-Methylpyridin-2-Yl)Ethanone adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Quality is verified against established specifications using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.