Description

6-Bromo-4-Methoxynicotinaldehyde is a versatile and high-purity brominated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and aldehyde functional groups, makes it an indispensable intermediate for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its reactive sites for structural diversification.
• Material Science: Serves as a monomer or functionalization agent in the creation of specialty polymers and organic electronic materials.
• Chemical Synthesis: Acts as a versatile electrophile in cross-coupling reactions (e.g., Suzuki, Stille) and a substrate for nucleophilic addition to the aldehyde group.
• Ligand & Catalyst Development: Employed in the design and synthesis of novel chelating ligands for catalytic systems.
• Academic & Contract Research: Essential reagent for methodological studies and custom synthesis projects in university and CRO laboratories.

Basic Information

Product Name	6-Bromo-4-Methoxynicotinaldehyde
CAS No.	1060805-10-8
Molecular Formula	C8H6BrNO2
Molecular Weight	230.04 g/mol
Synonyms	4-Methoxy-6-bromonicotinaldehyde; 6-Bromo-4-methoxypyridine-3-carboxaldehyde; 3-Formyl-6-bromo-4-methoxypyridine; 6-Bromo-4-methoxy-3-pyridinecarboxaldehyde; (6-Bromo-4-methoxypyridin-3-yl)methanal; 1060805-10-8; Aldehyde, 6-bromo-4-methoxynicotinal-
EINECS	Contact for details

Quality Control

Every batch of 6-Bromo-4-Methoxynicotinaldehyde is manufactured under strict quality management protocols and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, which include data from HPLC, NMR, and mass spectrometry. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.