Description

5-Amino-2-Chloroisonicotinaldehyde is a versatile and high-value pyridine derivative, serving as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both an amino and an aldehyde group on a chlorinated pyridine core, makes it indispensable for constructing complex heterocyclic scaffolds. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Building block for creating advanced herbicides, fungicides, and insecticides with specific modes of action.
• Ligand and Catalyst Development: Used to prepare specialized chelating ligands for metal-catalyzed reactions and coordination chemistry.
• Material Science Research: Employed in the development of organic electronic materials, such as novel polymers and small-molecule semiconductors.
• Chemical Biology Probes: Serves as a starting point for synthesizing fluorescent tags or activity-based probes for biological target identification.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name	5-Amino-2-Chloroisonicotinaldehyde
CAS No.	1060804-23-0
Molecular Formula	C6H5ClN2O
Molecular Weight	156.57 g/mol
Synonyms	2-Chloro-5-aminoisonicotinaldehyde; 2-Chloro-5-aminopyridine-4-carboxaldehyde; 4-Pyridinecarboxaldehyde, 5-amino-2-chloro-; 5-Amino-2-chloro-4-formylpyridine; 5-Amino-2-chloroisonicotinaldehyde; 5-Amino-2-chloro-4-pyridinecarboxaldehyde; 2-Chloro-5-aminopyridine-4-carbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 5-Amino-2-Chloroisonicotinaldehyde is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and cGMP manufacturing. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity (typically ≥97% by HPLC), and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This material is light-sensitive and easily oxidized; prolonged exposure to air or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.