Description

2,2,2-Trifluoro-1-(5-Methylpyridin-2-Yl)Ethanone is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in the introduction of a reactive trifluoroacetyl group adjacent to a substituted pyridine ring, enabling precise molecular modifications. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and insecticides that leverage the stability and bioactivity of the trifluoromethyl group.
• Ligand & Catalyst Development: Serves as a starting material for creating novel nitrogen-containing ligands for transition metal catalysis in fine chemical production.
• Material Science: Investigated as a monomer or modifier for synthesizing specialty polymers with unique optical or electronic properties.
• Fluorine Chemistry Research: A valuable reagent for studying structure-activity relationships (SAR) and introducing fluorinated motifs into complex molecules.

Basic Information

Product Name	2,2,2-Trifluoro-1-(5-Methylpyridin-2-Yl)Ethanone
CAS No.	1060801-56-0
Molecular Formula	C8H6F3NO
Molecular Weight	189.13 g/mol
Synonyms	2,2,2-Trifluoro-1-(5-methyl-2-pyridinyl)ethanone; 1-(5-Methylpyridin-2-yl)-2,2,2-trifluoroethanone; 5-Methyl-2-(trifluoroacetyl)pyridine; 2-(Trifluoroacetyl)-5-methylpyridine; 2-Acetyl-5-methylpyridine, 2,2,2-trifluoro-; Trifluoro(5-methyl-2-pyridinyl)methanone; CAS 1060801-56-0
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-1-(5-Methylpyridin-2-Yl)Ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.