Description

m-Peg4-Ch2-Aldehyde is a heterobifunctional polyethylene glycol (PEG) linker featuring a terminal aldehyde group. This compound is a critical reagent in bioconjugation and crosslinking chemistry, enabling the precise attachment of molecules to surfaces or other biomolecules. It is essential for researchers and manufacturers in the fields of biopharmaceuticals, diagnostics, and advanced materials development who require reliable, high-purity linkers for creating stable conjugates.

Application

• Bioconjugation and Crosslinking: Used to conjugate peptides, proteins, or antibodies to other molecules, surfaces, or nanoparticles via the reactive aldehyde group.
• PEGylation Reagent: Acts as a linker to introduce a hydrophilic PEG spacer, improving the solubility, stability, and pharmacokinetic properties of therapeutic biomolecules.
• Surface Functionalization: Employed to modify sensor chips, microarrays, and other solid supports with aldehyde groups for subsequent immobilization of biomolecules.
• Hydrogel Formation: Serves as a crosslinker in the synthesis of PEG-based hydrogels for tissue engineering and drug delivery applications.
• Antibody-Drug Conjugate (ADC) Development: Facilitates the site-specific conjugation of cytotoxic drugs to antibodies in ADC research and manufacturing.
• Diagnostic Assay Development: Used in the preparation of enzyme-linked immunosorbent assay (ELISA) components and other diagnostic reagents.

Basic Information

Item	Details
Product Name	m-Peg4-Ch2-Aldehyde
CAS No.	1059189-65-9
Molecular Formula	C15H28O7
Molecular Weight	320.38 g/mol
Synonyms	4,7,10,13-Tetraoxahexadecan-16-al; m-PEG4-CH2-CHO; 1,11-Dioxo-3,6,9-trioxa-12-azapentadecane; 16-Oxo-4,7,10,13-tetraoxahexadecan-1-oic acid derivative; Aldehyde-PEG4-acid; HOOC-PEG4-CH2-CHO (related acid form); Bifunctional PEG linker, aldehyde-terminated; Heterobifunctional PEG crosslinker
EINECS	Contact for details

Quality Control

Our m-Peg4-Ch2-Aldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and titration for functional group analysis, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and moisture absorption. Allow the product to equilibrate to room temperature in a desiccator before opening to avoid condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Aldehyde Content (Titration)	≥ 90% of theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.