Description

Boronic Acid, B-[2-[[Bis(1-Methylethyl)Amino]Carbonyl]-5-Bromophenyl]- is a specialized organoboron compound featuring a bromophenyl core and a diisopropylcarboxamide substituent, designed for advanced synthetic applications. Its primary value lies in its role as a key Suzuki-Miyaura cross-coupling reagent, enabling the efficient construction of complex biaryl structures critical in modern chemical research and development. This high-purity intermediate is essential for pharmaceutical chemists and agrochemical researchers focused on developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the biaryl motif is a common structural feature.
• Material Science: Serves as a precursor for organic electronic materials, including ligands for OLEDs and charge-transport molecules.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and activity-based protein profiling (ABPP) reagents that leverage boronic acid chemistry.
• Catalyst & Ligand Development: Acts as a starting material for creating novel palladium catalyst ligands and other metal-organic frameworks (MOFs).
• Academic & Contract Research: A valuable reagent for methodology development in organic synthesis laboratories within universities and CROs (Contract Research Organizations).

Basic Information

Item	Details
Product Name	Boronic Acid, B-[2-[[Bis(1-Methylethyl)Amino]Carbonyl]-5-Bromophenyl]-
CAS No.	1058129-82-0
Molecular Formula	C14H19BBrNO3
Molecular Weight	340.02 g/mol
Synonyms	5-Bromo-2-(diisopropylcarbamoyl)phenylboronic acid; (5-Bromo-2-((diisopropylcarbamoyl))phenyl)boronic acid; 2-((Diisopropylcarbamoyl)-5-bromophenylboronic acid; B-(2-(Bis(1-methylethyl)amino)carbonyl)-5-bromophenyl)boronic acid; 2-Carbamoyl-5-bromophenylboronic acid, N,N-diisopropyl-; Boronic acid, B-[2-[[bis(1-methylethyl)amino]carbonyl]-5-bromophenyl]-; 1058129-82-0; AKOS025310647
EINECS	Contact for details

Quality Control

Our production of Boronic Acid, B-[2-[[Bis(1-Methylethyl)Amino]Carbonyl]-5-Bromophenyl]- adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical synthetic applications. Each lot undergoes comprehensive analysis, including HPLC purity assessment and NMR structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, identity, and impurity profiles to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (argon or nitrogen) when opening the primary container to prevent degradation. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.