Description

n-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Methacrylamide is a high-value, functionalized monomer containing both a polymerizable methacrylamide group and a protected boronic acid moiety. This compound matters as a critical building block for synthesizing advanced polymeric materials with specific binding or sensing capabilities. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, advanced materials, and polymer science industries for creating specialty polymers, molecularly imprinted polymers (MIPs), and drug delivery systems.

Application

• Pharmaceutical Intermediate: Serves as a key monomer in the synthesis of drug delivery polymers and targeted therapeutic agents.
• Molecularly Imprinted Polymers (MIPs): Used to create highly selective polymer matrices for sensor development, separation science, and catalysis.
• Functional Coatings & Adhesives: Incorporated into specialty polymer formulations to introduce boronic acid functionality for cross-linking or binding to diol-containing surfaces.
• Bioconjugation & Diagnostic Reagents: Acts as a linker or functional handle for attaching polymers to biomolecules like sugars or glycoproteins.
• Advanced Material Research: Employed in academic and industrial R&D for developing novel stimuli-responsive (e.g., glucose-sensitive) hydrogels and smart materials.
• Organic Synthesis Building Block: Utilized in Suzuki-Miyaura cross-coupling reactions after deprotection of the boronic ester group.

Basic Information

Product Name	n-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Methacrylamide
CAS No.	1056904-42-7
Molecular Formula	C16H22BNO3
Molecular Weight	287.17 g/mol
Synonyms	3-Methacrylamidophenylboronic Acid Pinacol Ester; N-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methacrylamide; 3-Methacrylamido Phenylboronic Acid Pinacol Ester; Methacrylamide, N-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-; B-3-Methacrylamidophenylboronic Acid Pinacol Ester; 1056904-42-7; Boronic acid, B-[3-[(2-methyl-1-oxo-2-propen-1-yl)amino]phenyl]-, 4,4,5,5-tetramethyl-1,3,2-dioxaborolane-2-yl ester
EINECS	Contact for details

Quality Control

Our n-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Methacrylamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and structural identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your R&D and quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged use to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.