Description

2-Methyl-n-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-2-Propenamide is a high-value boronic ester derivative, a critical intermediate in modern synthetic organic chemistry. Its primary value lies in its role as a versatile building block for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise, scalable synthesis of novel compounds for drug discovery, crop protection, and organic electronics.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex biaryl motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Material Science: Serves as a monomer or precursor in the development of organic semiconductors, OLED materials, and conductive polymers.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for methodology development and library synthesis via palladium-catalyzed cross-coupling.
• Ligand and Catalyst Preparation: Can be utilized to synthesize novel bidentate or polydentate ligands for catalysis.
• Fine Chemical Production: Intermediate for the manufacture of specialty chemicals, dyes, and pigments.

Basic Information

Product Name	2-Methyl-n-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-2-Propenamide
CAS No.	1056904-41-6
Molecular Formula	C₁₆H₂₂BNO₃
Molecular Weight	287.16 g/mol
Synonyms	2-Methyl-N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]prop-2-enamide; 2-Propenamide, 2-methyl-N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)aniline acrylamide derivative; Methacryloyl pinacol phenylboronate; N-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methacrylamide
EINECS	Contact for details

Quality Control

Our 2-Methyl-n-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-2-Propenamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every lot and provided upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.