Description

4-(Thiophen-2-Yl)Phenylboronic Acid Pinacol Ester is a high-purity, synthetically valuable organoboron building block. This compound is essential for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern pharmaceutical and advanced materials research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries for constructing complex biaryl and heterobiaryl architectures.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates containing thiophene-phenyl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific heterocyclic structures.
• Material Science & OLED Development: Serves as a precursor for creating organic semiconductors, charge-transport materials, and emissive layers in OLED (Organic Light-Emitting Diode) devices.
• Ligand & Catalyst Preparation: Utilized in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A versatile reagent for academic and industrial research exploring new C-C bond-forming methodologies and novel molecular scaffolds.
• Polymer Chemistry: Can be incorporated into polymer backbones to impart specific electronic or physical properties to advanced polymeric materials.

Basic Information

Product Name	4-(Thiophen-2-Yl)Phenylboronic Acid Pinacol Ester
CAS No.	1056474-34-0
Molecular Formula	C₁₆H₁₉BO₂S
Molecular Weight	286.20 g/mol
Synonyms	2-(4-(Thiophen-2-yl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-(2-Thienyl)benzeneboronic Acid Pinacol Ester; [4-(Thiophen-2-yl)phenyl]boronic Acid Pinacol Ester; Pinacol 4-(Thiophen-2-yl)phenylboronate; 4-(2-Thienyl)phenylboronic Acid Pinacol Ester; 2-[4-(Thiophen-2-yl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 4-(Thiophen-2-Yl)Phenylboronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is analyzed via NMR, HPLC, and GC to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.