Description

2-Methyl-5-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)phenyl]-1,3,4-oxadiazole is a high-value, heterocyclic boronic ester derivative that serves as a critical building block in modern synthetic chemistry. Its core value lies in enabling the Suzuki-Miyaura cross-coupling reaction, a powerful and widely used method for forming carbon-carbon bonds under mild conditions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and efficient synthesis of complex organic molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing the 1,3,4-oxadiazole pharmacophore.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Material Science: Precursor for creating organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport materials.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing novel ligands and organometallic catalysts.
• Chemical Research: A versatile reagent in academic and industrial R&D for constructing complex, functionalized aromatic and heteroaromatic systems.
• Polymer Chemistry: Can be incorporated into polymer backbones to create specialty polymers with tailored electronic or mechanical properties.

Basic Information

Product Name	2-Methyl-5-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)phenyl]-1,3,4-Oxadiazole
CAS No.	1056456-24-6
Molecular Formula	C15H19BN2O3
Molecular Weight	286.14 g/mol
Synonyms	2-Methyl-5-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-1,3,4-oxadiazole; 5-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-2-methyl-1,3,4-oxadiazole; 2-Methyl-5-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1,3,4-oxadiazole; 4-(2-Methyl-1,3,4-oxadiazol-5-yl)phenylboronic acid pinacol ester; (4-(2-Methyl-1,3,4-oxadiazol-5-yl)phenyl)boronic acid pinacol ester; PINACOL 2-METHYL-5-(4-BORONIC ACID PHENYL)-1,3,4-OXADIAZOLE ESTER; CAS 1056456-24-6
EINECS	Contact for details

Quality Control

Our 2-Methyl-5-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)phenyl]-1,3,4-oxadiazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to cGMP and ISO standards guarantees a reliable supply of high-purity material for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.