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2-(1-Methyl-1H-Tetrazol-5-Yl)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine CAS NO 1056039-85-0
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CAS No.:1056039-85-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-(1-Methyl-1H-Tetrazol-5-Yl)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-value, multi-functional heterocyclic building block that combines a tetrazole ring with a pyridine-boronic ester pinacol group. This compound is critical for modern synthetic chemistry, enabling efficient cross-coupling reactions like Suzuki-Miyaura to construct complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and functional molecules.
Application
- Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly in medicinal chemistry programs.
- Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific heterocyclic scaffolds.
- Suzuki-Miyaura Cross-Coupling Reactions: The boronic ester functionality makes it an essential reagent for forming carbon-carbon bonds in complex organic synthesis.
- Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalysis and coordination chemistry.
- Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and conductive polymers.
- Chemical Biology Probes: Useful for creating tagged molecules and probes for studying biological systems and target engagement.
Basic Information
| Item | Details |
|---|---|
| Product Name | 2-(1-Methyl-1H-Tetrazol-5-Yl)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine |
| CAS No. | 1056039-85-0 |
| Molecular Formula | C14H19BN6O2 |
| Molecular Weight | 314.15 g/mol |
| Synonyms | 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(1-methyl-1H-tetrazol-5-yl)pyridine; 2-(1-Methyl-1H-tetrazol-5-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-(1-Methyl-1H-tetrazol-5-yl)pyridine-5-boronic acid pinacol ester; 5-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(1-methyltetrazol-5-yl)pyridine; Pyridine, 2-(1-methyl-1H-tetrazol-5-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)- |
| EINECS | Contact for details |
Quality Control
Our 2-(1-Methyl-1H-Tetrazol-5-Yl)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and structural integrity suitable for sensitive cross-coupling reactions. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency for your R&D and scale-up processes.
Storage
Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below under an inert atmosphere (argon or nitrogen) due to its moisture-sensitive and easily oxidized nature. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation and moisture ingress.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (HPLC) | Retention time corresponds to reference standard |
| Identification (NMR) | Spectrum consistent with structure |
| Purity (HPLC) | ≥ 97.0% |
| Water Content (KF) | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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