Description

Ethyl 2-(4-(trifluoromethyl)phenoxy)acetoacetate is a high-value fluorinated organic intermediate. This compound is significant for its role as a versatile building block in the synthesis of more complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by research and development chemists, process development scientists, and manufacturers in fine chemical and active pharmaceutical ingredient (API) production.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the trifluoromethylphenoxy moiety contributes to biological activity and stability.
• Liquid Crystal Material Precursor: Serves as a starting material for the development of fluorinated liquid crystals used in display technologies.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex ether and ester linkages in target molecules.
• Functional Material Development: Utilized in the creation of specialty polymers and coatings where fluorine incorporation enhances performance properties like chemical resistance and durability.

Basic Information

Product Name	Ethyl 2-(4-(trifluoromethyl)phenoxy)acetoacetate
CAS No.	1053657-44-5
Molecular Formula	C13H13F3O4
Molecular Weight	290.24 g/mol
Synonyms	Ethyl (4-(trifluoromethyl)phenoxy)acetoacetate; 2-(4-(Trifluoromethyl)phenoxy)-3-oxobutanoic acid ethyl ester; Acetoacetic acid, 2-[(4-(trifluoromethyl)phenoxy]-, ethyl ester; Ethyl 2-[(4-(trifluoromethyl)phenoxy]-3-oxobutanoate; 4-Trifluoromethylphenoxyacetoacetic acid ethyl ester; Ethyl α-(p-trifluoromethylphenoxy)acetoacetate; Ethyl 3-oxo-2-[4-(trifluoromethyl)phenoxy]butanoate
EINECS	Contact for details

Quality Control

Our Ethyl 2-(4-(trifluoromethyl)phenoxy)acetoacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.