Description

3-(Trifluoromethoxy)Benzenecarbothioamide is a high-purity fluorinated aromatic building block and a key synthetic intermediate. This compound is valued for its unique trifluoromethoxy-substituted aromatic core, which imparts desirable properties like enhanced metabolic stability and lipophilicity to target molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for use in medicinal chemistry and advanced material synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethoxy group can improve biological activity and environmental profile.
• Material Science Precursor: Serves as a specialized monomer or precursor for synthesizing advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and small-scale commercial batches.

Basic Information

Product Name	3-(Trifluoromethoxy)Benzenecarbothioamide
CAS No.	1053656-09-9
Molecular Formula	C8H6F3NOS
Molecular Weight	221.20 g/mol
Synonyms	3-(Trifluoromethoxy)benzothioamide; α,α,α-Trifluoro-m-anisothioamide; 3-(Trifluoromethoxy)thiobenzamide; m-Trifluoromethoxybenzothioamide; Benzenecarbothioamide, 3-(trifluoromethoxy)-; 3-Trifluoromethoxybenzene-1-carbothioamide
EINECS	Contact for details

Quality Control

Every batch of 3-(Trifluoromethoxy)Benzenecarbothioamide is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements of research and scale-up applications. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profiles via techniques such as HPLC, NMR, and MS is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.