Description

Methyl 2,4-Dichloro-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate is a high-value boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone technology for constructing complex biaryl and heterobiaryl structures. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise, scalable methods for carbon-carbon bond formation.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing complex aromatic and heteroaromatic scaffolds.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require specific chlorinated biaryl motifs.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology & Probe Development: Utilized in the creation of molecular probes and labeled compounds for biochemical and diagnostic applications.
• Academic & Industrial R&D: A versatile reagent for method development and exploring new synthetic pathways in organic chemistry laboratories.
• Ligand & Catalyst Preparation: Intermediate in the synthesis of specialized ligands and organometallic catalysts.

Basic Information

Item	Details
Product Name	Methyl 2,4-Dichloro-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate
CAS No.	1052647-70-7
Molecular Formula	C14H17BCl2O4
Molecular Weight	331.00 g/mol
Synonyms	2,4-Dichloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid methyl ester; Methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,4-dichlorobenzoate; 2,4-Dichloro-5-(pinacolatoboryl)benzoic acid methyl ester; 5-Borono-2,4-dichlorobenzoic acid methyl ester pinacol ester; (2,4-Dichloro-5-methoxycarbonylphenyl)boronic acid pinacol ester; Methyl 2,4-dichloro-5-(pinacolboronato)benzoate; 1052647-70-7; Methyl 2,4-dichloro-5-(pinacolatoboron)benzoate
EINECS	Contact for details

Quality Control

Our Methyl 2,4-Dichloro-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and residual solvent analysis to ensure it meets the high standards required for sensitive cross-coupling reactions. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.