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(2-Oxo2,3-Dihydro-1H-Indol-5-Yl)Boronic Acid CAS NO 1051316-38-1


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CAS No.:1051316-38-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(2-Oxo2,3-Dihydro-1H-Indol-5-Yl)Boronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its primary value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient synthesis of complex organic molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing novel active ingredients and functionalized heterocycles.

Application

  • Pharmaceutical Intermediate: A key synthon for constructing indole-based scaffolds in drug discovery and development programs.
  • Suzuki-Miyaura Cross-Coupling: Serves as a pivotal boronic acid reagent for forming carbon-carbon bonds to create complex biaryl and heterobiaryl structures.
  • Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides with enhanced efficacy.
  • Material Science Research: Employed in the synthesis of organic electronic materials, such as OLEDs and semiconductors, where precise molecular architecture is required.
  • Chemical Biology Probes: Facilitates the creation of labeled compounds and molecular probes for biochemical and diagnostic applications.
  • Catalyst & Ligand Development: Acts as a precursor for developing novel catalysts and ligands used in asymmetric synthesis.

Basic Information

Item Detail
Product Name (2-Oxo2,3-Dihydro-1H-Indol-5-Yl)Boronic Acid
CAS No. 1051316-38-1
Molecular Formula C8H8BNO3
Molecular Weight 176.97 g/mol
Synonyms 5-Indolinone-5-boronic acid; 5-Borono-2,3-dihydro-1H-indol-2-one; 2-Oxoindoline-5-boronic acid; 2,3-Dihydro-2-oxo-1H-indole-5-boronic acid; (2-Oxo-2,3-dihydro-1H-indol-5-yl)boronic acid; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)indolin-2-one (protected form); Oxindole-5-boronic acid
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Quality Control

Our (2-Oxo2,3-Dihydro-1H-Indol-5-Yl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed under an inert atmosphere to maintain stability and prevent moisture absorption.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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