Description

3-Fluoro-2-Methoxy-Benzenesulfonyl Chloride is a versatile and reactive organosulfur compound that serves as a critical building block in advanced organic synthesis. Its value lies in the sulfonyl chloride functional group, which readily undergoes nucleophilic substitution to form sulfonamides, sulfonate esters, and other valuable derivatives. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and fine chemicals that require a specific fluorinated and methoxylated aromatic scaffold.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially sulfonamide-based therapeutics targeting various diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the fluorine and methoxy groups confer specific biological activity and stability.
• Material Science Research: Building block for creating specialized polymers, ligands, or functional materials with tailored electronic or surface properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A high-purity intermediate supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	3-Fluoro-2-Methoxy-Benzenesulfonyl Chloride
CAS No.	1049729-85-2
Molecular Formula	C7H6ClFO3S
Molecular Weight	224.64 g/mol
Synonyms	3-Fluoro-2-methoxybenzenesulfonyl chloride; 2-Methoxy-3-fluorobenzenesulfonyl chloride; 1-Fluoro-2-methoxy-6-(chlorosulfonyl)benzene; Benzenesulfonyl chloride, 3-fluoro-2-methoxy-; 3-Fluoro-2-methoxybenzene-1-sulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-2-Methoxy-Benzenesulfonyl Chloride is produced and tested under strict quality management protocols to ensure high purity and consistency. Our products undergo rigorous quality testing, including advanced chromatographic analysis, to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.