Description

4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)Cyclohex-3-Ene-1-Carboxylic Acid Ethyl Ester is a high-value, advanced pharmaceutical intermediate featuring a protected boronic ester functional group. This compound is critical for enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern synthetic organic chemistry. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and materials science sectors for the development of novel active compounds and complex organic molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the formation of carbon-carbon bonds to construct biaryl and other conjugated systems essential for active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides with novel modes of action.
• Materials Science Research: Serves as a precursor for organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology & Probe Development: Utilized in creating molecular probes and labeled compounds for biochemical and diagnostic applications.
• Academic & Industrial R&D: A versatile reagent for method development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)Cyclohex-3-Ene-1-Carboxylic Acid Ethyl Ester
CAS No.	1049004-32-1
Molecular Formula	C15H25BO4
Molecular Weight	280.17 g/mol
Synonyms	Ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-cyclohexene-1-carboxylate; 3-Cyclohexene-1-carboxylic acid, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, ethyl ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-cyclohexenecarboxylic acid ethyl ester; 4-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-cyclohexenecarboxylic acid ethyl ester; Pinacol ester of 4-borono-3-cyclohexenecarboxylic acid ethyl ester.
EINECS	Contact for details

Quality Control

Our 4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)Cyclohex-3-Ene-1-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance for critical coupling reactions. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability and prevent hydrolysis of the boronic ester.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.