Description

1-Benzyl-1,2,3,6-Tetrahydropyridine-4-Boronic Acid Pinacol Ester is a high-value, organoboron building block essential for modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. This compound is critically needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those containing heterocyclic scaffolds.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic ester coupling partner for the introduction of the tetrahydropyridine moiety into target molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides requiring specific heterocyclic structures.
• Material Science: Potential building block for creating novel organic electronic materials and ligands for catalysis.
• Academic & Contract Research: Fundamental reagent for methodological development and exploratory synthesis in academic and CRO laboratories.

Basic Information

Product Name	1-Benzyl-1,2,3,6-Tetrahydropyridine-4-Boronic Acid Pinacol Ester
CAS No.	1048976-83-5
Molecular Formula	C18H26BNO2
Molecular Weight	299.22 g/mol
Synonyms	1-Benzyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,6-tetrahydropyridine; 1-Benzyl-1,2,3,6-tetrahydro-4-pyridineboronic acid pinacol ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(phenylmethyl)-1,2,3,6-tetrahydropyridine; 1-Benzyl-4-(pinacolboronato)-1,2,3,6-tetrahydropyridine; N-Benzyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,6-tetrahydropyridine
EINECS	Contact for details

Quality Control

Our 1-Benzyl-1,2,3,6-Tetrahydropyridine-4-Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and scale-up applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.