Description

Methyl 5-Borono-2-Methylbenzoate is a high-purity boronic acid ester derivative, a key intermediate in modern synthetic organic chemistry. Its primary value lies in its utility as a versatile building block for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biphenyl or substituted phenyl motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Material Science Research: Serves as a precursor for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where controlled molecular architecture is paramount.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for transition metal catalysis and organoboron reagents for further functionalization.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and bio-conjugates for studying biological processes.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthetic routes and scale-up projects.

Basic Information

Product Name	Methyl 5-Borono-2-Methylbenzoate
CAS No.	1048330-10-4
Molecular Formula	C9H11BO4
Molecular Weight	193.99 g/mol
Synonyms	5-(Methoxycarbonyl)-2-methylphenylboronic acid; Methyl 2-Methyl-5-boronobenzoate; 2-Methyl-5-(methoxycarbonyl)benzeneboronic acid; 5-Borono-2-methylbenzoic acid methyl ester; (5-(Methoxycarbonyl)-2-methylphenyl)boronic acid; 2-Methyl-5-carbomethoxyphenylboronic acid; Benzoic acid, 5-borono-2-methyl-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 5-Borono-2-Methylbenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistent performance in coupling reactions. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting cGMP and ISO 9001 compliance for our pharmaceutical and industrial partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.