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Lithium (5-Cyanopyridin-2-Yl)Triisopropoxyborate CAS NO 1048030-52-9


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CAS No.:1048030-52-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Lithium (5-Cyanopyridin-2-Yl)Triisopropoxyborate is a specialized organoboron reagent, specifically a lithium boronate complex, widely used in modern synthetic chemistry. Its core value lies in enabling efficient and selective cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This high-purity intermediate is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where precision and reliability are paramount.

Application

  • Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl/heteroaryl halides and boronic acid derivatives.
  • Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for constructing biaryl and heterobiaryl motifs common in drug molecules.
  • Agrochemical Compound Development: Employed in the synthesis of novel herbicides, fungicides, and insecticides that require specific heterocyclic frameworks.
  • Material Science & OLED Precursors: Serves as a building block for creating organic light-emitting diode (OLED) materials and other functional organic electronic compounds.
  • Ligand and Catalyst Preparation: Utilized in the synthesis of novel ligands and organometallic catalysts for asymmetric synthesis.
  • Chemical Biology & Probe Development: Acts as a versatile handle for bioconjugation and the synthesis of molecular probes for biological target identification.

Basic Information

Product Name Lithium (5-Cyanopyridin-2-Yl)Triisopropoxyborate
CAS No. 1048030-52-9
Molecular Formula C15H24BLiN2O3
Molecular Weight 298.12 g/mol
Synonyms Lithium (5-Cyanopyridin-2-yl)triisopropoxyborate; 2-(5-Cyanopyridin-2-yl)-4,4,5,5-tetraisopropoxy-1,3,2-dioxaborolane lithium salt; 5-Cyanopyridine-2-boronic acid triisopropyl ester lithium complex; 2-Pyridineboronic acid, 5-cyano-, triisopropyl ester, lithium complex; Lithium 5-cyanopyridine-2-triisopropoxyborate; (5-Cyanopyridin-2-yl)triisopropoxyboron lithium salt
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Quality Control

Our Lithium (5-Cyanopyridin-2-Yl)Triisopropoxyborate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, identity, and impurity profiles. We support development and production needs with specifications that can meet the rigorous standards of cGMP and ISO guidelines for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (argon or nitrogen) to maintain stability and purity. Keep away from incompatible materials such as strong acids and oxidizing agents.

Specification

Item Specification
Appearance White to off-white powder or crystalline solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 1.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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