Description

1-Ethyl-4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole is a high-purity, functionalized pyrazole boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling efficient cross-coupling reactions, particularly the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, ligand synthesis, and the development of functional organic molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Material Science: Precursor for creating organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Ligand and Catalyst Development: Serves as a versatile scaffold for constructing specialized ligands used in homogeneous catalysis.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying biological processes and target identification.
• Polymer Chemistry: Monomer or cross-linking agent in the synthesis of specialty polymers with tailored properties.

Basic Information

Item	Details
Product Name	1-Ethyl-4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole
CAS No.	1047636-01-0
Molecular Formula	C12H21BN2O2
Molecular Weight	236.12 g/mol
Synonyms	1-Ethyl-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-ethyl-4-methyl-1H-pyrazole; 1-Ethyl-4-methyl-1H-pyrazole-5-boronic acid pinacol ester; 1-Ethyl-4-methylpyrazole-5-boronic acid pinacol ester; 1H-Pyrazole-5-boronic acid, 1-ethyl-4-methyl-, 1,3,2-dioxaborolane deriv.
EINECS	Contact for details

Quality Control

Our 1-Ethyl-4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are available upon request. We are committed to meeting the stringent requirements of research and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.