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6-Dimethylamino-4-Methylpyridine-3-Boronic Acid Pinacol Ester CAS NO 1046862-09-2


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CAS No.:1046862-09-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

6-Dimethylamino-4-Methylpyridine-3-Boronic Acid Pinacol Ester is a sophisticated, high-purity boronic ester derivative, a critical building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone technology for constructing complex molecules. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients, as well as in materials science for creating novel organic electronic compounds.

Application

  • Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
  • Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides requiring specific heterocyclic architectures.
  • Material Science Research: Serves as a precursor for creating organic semiconductors, ligands for catalysts, and novel polymers with tailored electronic properties.
  • Suzuki-Miyaura Cross-Coupling Reactions: The primary application, facilitating the efficient and selective formation of biaryl and other C-C bonds in complex molecule assembly.
  • Chemical Biology & Probe Development: Utilized in constructing molecular probes and tools for studying biological processes and target engagement.
  • Academic & R&D Laboratories: A valuable reagent for methodological development and the synthesis of novel chemical entities in discovery chemistry.

Basic Information

Product Name 6-Dimethylamino-4-Methylpyridine-3-Boronic Acid Pinacol Ester
CAS No. 1046862-09-2
Molecular Formula C14H21BN2O2
Molecular Weight 260.15 g/mol
Synonyms 4-Methyl-6-(dimethylamino)pyridine-3-boronic acid pinacol ester; (6-(Dimethylamino)-4-methylpyridin-3-yl)boronic acid pinacol ester; 3-Borono-6-dimethylamino-4-methylpyridine pinacol ester; 6-Dimethylamino-4-methyl-3-pyridineboronic acid pinacol ester; Pinacol (6-(dimethylamino)-4-methylpyridin-3-yl)boronate; 1046862-09-2; DMAP-BPin derivative
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Quality Control

Our 6-Dimethylamino-4-Methylpyridine-3-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee batch-to-batch consistency and support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal stability and purity.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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