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4-Bromo-2-Chlorophenylboronic Acid CAS NO 1046861-20-4


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CAS No.:1046861-20-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-Bromo-2-Chlorophenylboronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to develop active pharmaceutical ingredients (APIs), novel crop protection agents, and specialty polymers.

Application

  • Pharmaceutical Intermediate: A key synthon for constructing biaryl structures found in various drug candidates and active pharmaceutical ingredients (APIs).
  • Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific halogenated biphenyl motifs.
  • Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs and semiconductors.
  • Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for transition metal catalysis and organoboron reagents.
  • Chemical Biology & Proteomics: Utilized in the development of molecular probes and inhibitors for studying biological pathways.
  • Custom Synthesis & Contract Manufacturing: A fundamental reagent for custom synthesis houses serving the life sciences and fine chemical industries.

Basic Information

Product Name 4-Bromo-2-Chlorophenylboronic Acid
CAS No. 1046861-20-4
Molecular Formula C6H5BBrClO2
Molecular Weight 235.27 g/mol
Synonyms (4-Bromo-2-chlorophenyl)boronic acid; 2-Chloro-4-bromophenylboronic acid; B-(4-Bromo-2-chlorophenyl)boronic acid; 4-Bromo-2-chlorobenzeneboronic acid; 1046861-20-4; Boronic acid, B-(4-bromo-2-chlorophenyl)-; AKOS025310947
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Quality Control

Our 4-Bromo-2-Chlorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥97.0% (Area %)
Water Content (KF) ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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