Description

1,3-Dimethyl-1H-Pyrazole-4-Boronic Acid,Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key reagent in Suzuki-Miyaura cross-coupling reactions for constructing biaryl and heteroaryl scaffolds in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require specific pyrazole-containing structures.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of enzyme inhibitors or molecular probes.
• Catalyst & Ligand Development: Serves as a precursor for creating novel organoboron catalysts and specialized ligands for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and non-commercial research quantities.

Basic Information

Item	Details
Product Name	1,3-Dimethyl-1H-Pyrazole-4-Boronic Acid,Pinacol Ester
CAS No.	1046832-21-6
Molecular Formula	C11H19BN2O2
Molecular Weight	222.10 g/mol
Synonyms	1,3-Dimethyl-1H-pyrazol-4-ylboronic acid pinacol ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-dimethyl-1H-pyrazole; 1,3-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 1,3-Dimethyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 1,3-Dimethylpyrazole-4-boronic acid pinacol ester; DMHP-Bpin
EINECS	Contact for details

Quality Control

Our 1,3-Dimethyl-1H-Pyrazole-4-Boronic Acid,Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 13C, 11B), HPLC, and GC analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.