Description

2-(4,5-Dihydrofuran-3-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity, versatile boronic ester building block essential for modern synthetic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds in pharmaceutical and advanced material research. This compound is specifically designed for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries who require reliable, high-quality intermediates for synthesizing novel compounds and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that require specific aryl- or heteroaryl-boronate components.
• Material Science & OLED Development: Serves as a precursor for constructing conjugated polymers and organic light-emitting diode (OLED) materials that demand precise molecular architecture.
• Chemical Biology & Probe Development: Employed in synthesizing bioconjugates and molecular probes for diagnostic and research applications.
• Academic & Industrial R&D: A fundamental reagent for method development and exploring new synthetic pathways in organic chemistry laboratories.
• Ligand and Catalyst Synthesis: Useful for preparing sophisticated ligands and organometallic catalysts used in asymmetric synthesis.

Basic Information

Product Name	2-(4,5-Dihydrofuran-3-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1046812-03-6
Molecular Formula	C12H19BO3
Molecular Weight	222.09 g/mol
Synonyms	3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,5-dihydrofuran; 2,5-Dihydro-3-furanboronic acid pinacol ester; 2-(2,5-Dihydro-3-furanyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-(Pinacolatoboryl)-2,5-dihydrofuran; Dihydrofuran-3-ylboronic acid pinacol ester; 2,5-Dihydrofuran-3-boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-(4,5-Dihydrofuran-3-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high purity and consistency suitable for sensitive cross-coupling applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every lot upon request, providing full traceability and compliance with internal and customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥95% (Typical 97-99%)
Water Content (KF)	<0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.