Description

2-(3,4-Dihydro-2H-Pyran-5-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity, advanced boronic ester building block essential for modern synthetic chemistry. This compound matters because it serves as a critical intermediate in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. Pharmaceutical researchers, agrochemical developers, and material scientists need it for creating novel active ingredients and functional polymers. Its unique structure combines a protected dihydropyran moiety with a stable pinacol boronate, offering versatile reactivity for targeted synthesis.

Application

• Pharmaceutical Intermediate: Key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of advanced crop protection agents and herbicides.
• Material Science: Serves as a monomer or functionalization agent in the creation of specialty polymers and organic electronic materials.
• Chemical Research: A versatile reagent in academic and industrial R&D for exploring new organic transformations and catalytic cycles.
• Ligand and Catalyst Development: Employed in the synthesis of complex ligands and organometallic catalysts.
• Fine Chemical Production: Intermediate for manufacturing high-value, complex fine chemicals and flavors/fragrances.

Basic Information

Product Name	2-(3,4-Dihydro-2H-Pyran-5-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1046811-99-7
Molecular Formula	C11H19BO3
Molecular Weight	210.08 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2H-pyran; 2-(3,4-Dihydro-2H-pyran-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 5-(Pinacolatoboryl)-3,4-dihydro-2H-pyran; DHP-Pinacolborane; 3,4-Dihydro-2H-pyran-5-ylboronic acid pinacol ester; 5-Borono-3,4-dihydro-2H-pyran pinacol ester
EINECS	Contact for details

Quality Control

Our 2-(3,4-Dihydro-2H-Pyran-5-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing identity, assay, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) to prevent moisture absorption and decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.