Description

1-Methyl-4-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-3-Cyclohexen-1-Yl]-Piperazine is a sophisticated, high-value organoboron building block designed for advanced pharmaceutical and agrochemical research. This compound is critical for enabling Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors to synthesize novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Research: Used to create new active ingredients for crop protection agents, including herbicides, fungicides, and insecticides.
• Material Science: Serves as a precursor for the development of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology: Employed in the synthesis of molecular probes and bioconjugates for target identification and validation studies.
• Process Chemistry: Enables scalable, efficient routes for the commercial production of complex molecules via palladium-catalyzed cross-coupling.
• Academic & Contract Research: Essential for methodology development and exploratory synthesis in university and CRO laboratories.

Basic Information

Product Name	1-Methyl-4-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-3-Cyclohexen-1-Yl]-Piperazine
CAS No.	1046793-62-7
Molecular Formula	C17H31BN2O2
Molecular Weight	306.25 g/mol
Synonyms	1-Methyl-4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-en-1-yl)piperazine; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-cyclohexen-1-yl-1-methylpiperazine; 1-Methyl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-cyclohexen-1-yl]piperazine; 1-Methyl-4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-enyl)piperazine; 1-Methyl-4-(4-(tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-en-1-yl)piperazine; 1046793-62-7; Pinacol 1-Methyl-4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-enyl)piperazine-1-ylboronate
EINECS	Contact for details

Quality Control

Our production of 1-Methyl-4-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-3-Cyclohexen-1-Yl]-Piperazine adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical synthetic applications. All materials undergo comprehensive analytical characterization, including HPLC, NMR (1H, 13C, 11B), and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles. We support compliance with REACH, FDA guidelines for drug substances, and other relevant global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent moisture absorption and decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.