Description

3-(2,5-Difluorophenyl)Piperidine is a high-value, fluorinated piperidine derivative serving as a critical building block in advanced organic synthesis. This compound is essential for medicinal chemistry research and pharmaceutical development, particularly in the creation of novel drug candidates targeting central nervous system (CNS) disorders. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for its unique structural motif that can modulate biological activity and improve metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for neurological and psychiatric therapeutics.
• Medicinal Chemistry Scaffold: Used as a core structure or substituent for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Research: Employed in the synthesis of novel pesticides and herbicides, leveraging the fluorine atoms for enhanced bioactivity and environmental persistence.
• Ligand Synthesis: Useful in the preparation of specialized ligands for catalysis and molecular recognition applications.
• Fine Chemical Production: Serves as a precursor for other complex, fluorinated organic molecules used in material science and electronics.

Basic Information

Product Name	3-(2,5-Difluorophenyl)Piperidine
CAS No.	1044768-90-2
Molecular Formula	C11H13F2N
Molecular Weight	197.22 g/mol
Synonyms	3-(2,5-Difluorophenyl)piperidine; 2,5-Difluoro-3-piperidinylbenzene; 1-(2,5-Difluorophenyl)-3-piperidine; Piperidine, 3-(2,5-difluorophenyl)-; 1044768-90-2; 3-(2,5-Difluorophenyl)piperidine hydrochloride (salts may have separate CAS); 2,5-Difluoro-β-piperidinylbenzene
EINECS	Contact for details

Quality Control

Our 3-(2,5-Difluorophenyl)Piperidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for high-purity grades. Keep away from strong oxidizers.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.