Description

3-[2-(Trifluoromethyl)Phenyl]Piperidine is a high-value, fluorinated piperidine derivative, serving as a critical building block in modern organic synthesis. Its unique structure, featuring a trifluoromethylphenyl group, is engineered to impart desirable properties such as enhanced metabolic stability and lipophilicity to target molecules. This advanced intermediate is primarily utilized by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in central nervous system (CNS) and metabolic disease therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the trifluoromethyl group can improve biological activity and environmental stability.
• Ligand & Catalyst Development: Employed in organometallic chemistry for constructing complex ligands used in asymmetric catalysis.
• Material Science Research: Acts as a precursor for specialty polymers and advanced organic materials requiring specific fluorine-containing motifs.
• Chemical Biology Probes: Useful for synthesizing molecular probes to study enzyme function and biological pathways.

Basic Information

Product Name	3-[2-(Trifluoromethyl)Phenyl]Piperidine
CAS No.	1044765-43-6
Molecular Formula	C12H14F3N
Molecular Weight	229.24 g/mol
Synonyms	3-(2-(Trifluoromethyl)phenyl)piperidine; 2-(Trifluoromethyl)-3-piperidin-3-ylbenzene; 3-Piperidin-3-yl-α,α,α-trifluoro-o-xylene; 1-[2-(Trifluoromethyl)phenyl]-3-piperidine; 3-(2-Trifluoromethylphenyl)piperidine; 1044765-43-6
EINECS	Contact for details

Quality Control

Every batch of 3-[2-(Trifluoromethyl)Phenyl]Piperidine is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development applications. A detailed Certificate of Analysis (COA), including results from HPLC, NMR, and GC-MS, is supplied with each shipment to guarantee identity, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.