Description

5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Isophthalic Acid is a high-purity, functionalized aromatic building block containing a pinacol boronate ester group. This compound is a critical intermediate in modern synthetic chemistry, enabling precise carbon-carbon bond formation via cross-coupling reactions. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing complex drug candidates, including kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the boronic ester moiety allows for the introduction of specific aromatic fragments.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for creating novel electron-transport materials and emissive layer components in display and lighting technologies.
• Polymer & Material Science: Incorporated into monomers for synthesizing specialty polyesters, polyamides, and other high-performance polymers with tailored properties.
• Ligand & Catalyst Development: Employed in the synthesis of novel bidentate or tridentate ligands for transition metal catalysis.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D in organic synthesis, medicinal chemistry, and chemical biology.

Basic Information

Item	Detail
Product Name	5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Isophthalic Acid
CAS No.	1041434-13-2
Molecular Formula	C15H19BO6
Molecular Weight	306.12 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzene-1,3-dicarboxylic Acid; 5-(Pinacolatoboryl)isophthalic Acid; 5-Boronoisophthalic Acid Pinacol Ester; 5-Isophthalic Acid Pinacol Boronate; 5-Carboxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic Acid; Isophthalic Acid-5-boronic Acid Pinacol Ester
EINECS	Contact for details

Quality Control

Every batch of 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Isophthalic Acid is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including NMR, HPLC, and elemental analysis, to ensure compliance with exacting purity and identity specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.