Description

1,3,2-Dioxaborolane, 2-(1-Cyclododecen-1-Yl)-4,4,5,5-Tetramethyl- is a specialized organoboron reagent featuring a cyclic dioxaborolane (pinacol boronate ester) group tethered to a large cyclododecene ring. This compound is valued for its role as a versatile synthetic intermediate in advanced organic transformations, particularly in cross-coupling reactions. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key boron reagent for forming carbon-carbon bonds between the cyclododecenyl moiety and aryl/vinyl halides, enabling the synthesis of complex, sterically hindered molecules.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs), especially for introducing the bulky, lipophilic cyclododecene group to modulate biological activity and pharmacokinetic properties.
• Agrochemical Product Development: Serves as a building block for creating novel fungicides, herbicides, or plant growth regulators with tailored properties.
• Material Science & Polymer Chemistry: Employed in the synthesis of functional monomers or precursors for specialty polymers, liquid crystals, or organic electronic materials.
• Catalyst & Ligand Development: Acts as a precursor for synthesizing novel ligands or organometallic catalysts used in asymmetric synthesis and homogeneous catalysis.
• Chemical Biology & Probe Development: Useful for incorporating the hydrophobic cyclododecene tag into molecular probes for studying protein-lipid interactions or membrane biology.

Basic Information

Product Name	1,3,2-Dioxaborolane, 2-(1-Cyclododecen-1-Yl)-4,4,5,5-Tetramethyl-
CAS No.	1041002-96-3
Molecular Formula	C18H33BO2
Molecular Weight	292.27 g/mol
Synonyms	2-(Cyclododec-1-en-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (1-Cyclododecen-1-yl)pinacol boronate; Cyclododec-1-en-1-ylboronic acid pinacol ester; 1-Cyclododecenylboronic acid pinacol ester; Cyclododecenyl pinacol boronate; Pinacol (1-cyclododecen-1-yl)boronate; (Cyclododec-1-enyl)BPin
EINECS	Contact for details

Quality Control

Our 1,3,2-Dioxaborolane, 2-(1-Cyclododecen-1-Yl)-4,4,5,5-Tetramethyl- is manufactured under strict quality protocols. Each batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ¹¹B) for structural confirmation and HPLC/GC for purity assessment, to ensure it meets exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and prolong shelf-life. The container should be kept in a cool, dry, and well-ventilated area, away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid or viscous liquid
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥95% (Typical 97-99%)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.