Description

4'-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-[1,1'-Biphenyl]-4-Carbaldehyde is a high-value, bifunctional organic building block featuring both a formyl group and a protected boronic ester. This compound matters as a critical intermediate in modern synthetic chemistry, enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions. Pharmaceutical, agrochemical, and advanced material researchers need it for constructing complex molecular architectures, such as active pharmaceutical ingredients (APIs) and organic electronic materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to create advanced active ingredients for crop protection products.
• Material Science: Building block for organic light-emitting diodes (OLEDs), liquid crystals, and conductive polymers.
• Academic & Industrial R&D: Essential reagent for method development and exploring new synthetic pathways in organic chemistry.
• Chemical Biology: Utilized in the development of molecular probes and bioconjugation reagents.
• Fine Chemical Production: Intermediate for manufacturing specialty chemicals with high added value.

Basic Information

Product Name	4'-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-[1,1'-Biphenyl]-4-Carbaldehyde
CAS No.	1040424-52-9
Molecular Formula	C19H21BO3
Molecular Weight	308.18 g/mol
Synonyms	4-Formyl-4'-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,1'-biphenyl; [1,1'-Biphenyl]-4-carboxaldehyde, 4'-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)biphenyl-4-carbaldehyde; 4'-Pinacolatoboryl-[1,1'-biphenyl]-4-carbaldehyde; 4-Formylphenylboronic acid pinacol ester; 4-(4-Formylphenyl)phenylboronic acid pinacol ester; 4'-BPin-Biphenyl-4-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 4'-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-[1,1'-Biphenyl]-4-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.